The Synthesis Of New Poly(Silyl Ester)s Via Condensation Of Di-Tert-Butyl Ester Of Dicarboxylic Acid With Chlorosilane

Poly(silyl ester)s which have large numbers of silyl ester bonds in the polymer backbones could break down into small-molecule byproducts, so poly(silyl ester)s could been a new type of degradable material. Nucleophilic attack on acyloxysilane groups can occur at both the silicon atom and the carbonyl carbon. As substituents with increasing steric bulk or increasing electron-donating capabilities are attached to the silicon, an increasing amount of attack occurs at the carbonyl. Otherwise, an increasing amount of attack occurs at the silicon atom. So the degradation rate could vary by changing the substituents attached to the silicon atoms and the composition of the backbone. The degradable rate of the poly(silyl ester)s was variable and predictable degradation behavior and the degradation products from poly(silyl ester)s were innoxious or approximately innoxious, so the applications such as matrices for drug release, temporary coatings, temporary adhesives, or other purposes are envisioned.The study about the synthesis routes and the properties of poly(silyl ester)s have received considerable interest. Several routes have been reported by Karen L. Wooley to synthesize poly(silyl ester)s including transsilylation of AA/BB monomer systems, transsilylation of AB monomer systems, hydrosilylation of AB monomer systems and cross-dehydro coupling-based polymerizations of AB and AB_n monomer systems.