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Construction A Vector Of SiRNA To PTI-1 Gene And The Study Of Inhibiting The Growth Of Transfected Human Prostate Cancer Cell Lines

Posted on:2007-10-13Degree:DoctorType:Dissertation
Country:ChinaCandidate:L YuFull Text:PDF
GTID:1104360185470987Subject:Surgery
Abstract/Summary:PDF Full Text Request
The incidence and mortality of adenocarcinoma of the prostate continue to rise and will continue to pose a major public health problem. Prostate cancer is the second most common cause of cancer deaths in men. Despite progress in diagnosis and local therapy, fundamental questions remain with regard to the etiology, prevention, and treatment of prostate cancer. Our knowledge of prostate adenocarcinoma remains significantly less than of most other neoplasms. A variety of clinical, biochemical, pathological and imaging tools are currently involved in the diagnosis and staging of condition which all require fairly bulky tumor regrowth before discovery. Finding a more sensitivity marker or oncogenic potential gene will provide us a useful tool to diagnose and cure prostate carcinoma.PTI-1 (Prostate carcinoma tumor-inducing gene 1,PTI-1) was originally...
Keywords/Search Tags:prostate cancer, prostate tumor inducing gene 1 (PTI-1), transfection, vector, RNA interference
PDF Full Text Request
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