The Primary Epidemic Investigation And Some Relative Basic Study On Polycystic Ovary Syndrome

Section Ⅰ The primary epidemic investigation of prevalence and characteristics of Chinese women with polycystic ovary syndromeOBJECTIVE To investigate the prevalence and characters of polycystic ovary syndrome (PCOS) in Chinese from general Han ethnic population in Jinan city by ESHRE/ASRM criteria; to study this criteria's feasibility to Han ethnic PCOS diagnosis. METHODS With cluster sampling epidemic method, 1027 women from Jinan city were investigated by ESHRE/ASRM criteria. The prevalence, clinical and metabolitic characters on PCOS were analysed. RESULTS (1) According to the ESHRE/ASRM criteria, 85 PCOS patients were diagnosed from whole investigated population, the prevalence of PCOS in general Han population in Jinan city is accounted for 6.46%. (2) Single variable statistic and multinomial logistic regression analysis results show oligomenorrhea, irregularly menstruation, ovarian volume, follicle number in 2-9 mm diameter,hirsutism, acne, T, free androgen index(FAI) are the main statistic variables for PCOS's diagnosis which just meet the need of ESHRE/ASRM criteria., (3) Among all PCOS patients, check rates of Oligo-ovulation, PCO, biochemical and clinical of androgen excess signs for PCOS are 89.4%, 72.94%, 57.65% and 38.8% (1.18% hirsutism by F-G≥6 and 38.8% acne)respectively; check rates by all two criteria are 100%,but different group have different check rate; 48.2% and 11.8% patients meet 3 criteria but respectively with one of and both of androgen excess signs(clinical / biochemical); By our investigated F-G score ≥2 score standard, hirsutism is account for 37.65% in PCOS patients from general population. (4) PCOS is distribute in the ≤35 years old population groups; ageing, labor can influence each PCOS diagnostic criterion. (5) Infertility and obesity are accounted for 7.06% and 8.23% in general PCOS population, insulin...