| There is an increasing need for bone replacement and repair with the purpose of curing the bone-related diseases and improving the life quality of the patients.This present work is financially supported by the Nation Natural Science Foundation of China(No.50235020), and it is a part of the basic study of the Foundation item. The final purpose of the work is to construct a bioactive Ti metal replacement of bone or repair the bone in a more efficient way.The replacing or repairing implants will be bioactive and have proper early load capacity,which will finally form a composite bone (i.e. a combination of non-life Ti metal and life bone) in a living organism.The contents and the results of this work are as follows:(1)Synthetic bioceramic hydroxyapatite(HA,Ca10(PO4)6(OH)2) are widely used for repair or replacement of fractured bone tissue due to its similar chemical and crystallographic structure to natural bone. In this part, hydroxyapatite powders and the films were prepared using two alcohol-based sol-gel processes. Phosphoric acid and organic triethyl phosphite were used as phosphorus precursors, respectively, and calcium nitrate as calcium precursor. Both as-synthesized samples were dried at 80℃and then calcined at various temperatures. The XRD, FT-IR DTA/TGA and FE-SEM were employed to investigate their different characteristics, and a comparison among the two as-synthesized powders and hydroxyapatite of human tibial cortical bone was made. The two sols were spin-coated onto Ti6Al4V substrates, and then annealed at 500℃.The different surface morphologies were investigated by FE-SEM and AFM.The results show that there existed some obvious differences in the... |
PDF Full Text Request