Objective Select given BIS as anesthetic terminal point index, assess the feasibility of TCI propofol in the cardiovascular anesthesia, and find out a safe anesthetic scheme guiding the clinic cardiovascular "fast track anesthesia".Methods Ninety-five, adult, ASAII-III patients scheduled for selective heart surgery were divided into four groups. Among these patients, thirty patients of HVR were divided into two groups randomly( group 1-1 and group 1-2), which were observed anesthetic induction merely, each group was fifteen patients, the aim BIS was 50-59 and 40-49 respectively. Another thirty-five HVR patients was group V, thirty-CABG patients was group C. Group V and group C were observed whole anesthetic stage, and the aim BIS was 45-55. The initial propofol TCI plasma concentration was 0.5μg/ml, increased step by step until BIS was in target range, then keep it. Supplementary administrated fentanyl 5μg/kg before tracheal intubation, skin incision and stormy closure respectively. Observed the change of hemodynamics, recorded the data of propofol plasma...
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