The Mechanism Of Micro-current Resumes Hindlimbs Function Of Rats After Their Spinal Cord Were Transected

The morbidity of the paraplegia and quadraplegia patients caused by spinal cord injuried (SCI) is about 20-40 persons per million persons every year. These patients often lose their labour and life ability. It is a serious society problem that can not be ignored. How to relieve the pain of the patiens and restore the function of the spinal cord injuried in a great degree? This is the heated issues in the world and is also a direction of SCI study laid down by international spinal cord trust company.The regeneration of the transected axons is the key way in the function recovering of spinal cord injuried, so, if they were connected with the target nerve fiber again by treament, the body will be controlled by the brain.The glia cells are the most members of central never system. What will the glia cells change in trauma section and around? Whether can the micro-current restrain the scar hyperplasia caused by the glia cells and lead the axons traversing the scar obstruct and connecting with the target nerve cell again? So, the micro-current was used to treat the wistar rats after their spinal cord were transected in this study, then the trauma section of the spinal cord was taken out and the RT-PCRn Western Blot and immunohistochemical methods were used to examine the expression of GFAP, Nogo and Gap-43 in this tissuse, thereby the mechanism of the treatment of micro-current on injuried spinal cord is deduced and a new theory on this treatment will be supply.Objective:To illustrate the mechanism of the treatment of micro-current on spinal cord injuried via showing the change of the expression of GFAP,...