Clinical Applied Study Of Endovascular Interventional Treatment For Cervicocerebral Atherosclerosis

Research backgroundMorphological research of cervicocerebral atherosclerosis(CCAS) is important in understanding the possible pathogenesis of stroke,evaluating stroke risk, deciding therapeutic strategy and evaluating risks relating to endovascular therapy.Main interest of morphological study of CCAS is the extracranial bifurcation of internal carotid artery,wheras there are only few studies were performed on the intracranial artery.Present studies focus on the relationship between the degree of stenosis of CCAS lesion and stroke risk,while less studies on the relationship between ulceration of CCAS lesion and stroke risk. Studies on other morphological characteristics of CCAS are rare. To our knowledge, there is no study of angioarchitectural determinants of CCAS and the relationship with stroke. Risks of endovascular treatment of CCAS is closely related to the morphological factors of lesions.According to current endovascular treatment studies, the incidence of stroke rate and mortality range from 9.5%-50%. Such a great difference reflects poor understanding of CCAS in nature.It is essential to establish a reasonable endovarscular strategy on CCAS lesion. More and more asymptomatic CCAS are diagnosed with the advances of imaging technique.So it is more and more important to evaluate the stroke risks of CCAS lesion for selecting patients into risking endovascular treatment group. The degree of stenosis is the main and sometimes even the only factor in the temporary indication of endovascular stenting of CCAS.In this therapeutic strategy,the hypoperfusion is the only concerning regarding the...