Prognostic Factors For Postoperative Symptomatic Vasospasm In Patients With Intracranial Aneurysm

Objective The purpose of this study was to describe prognostic factors for symptomatic vasospasm in patients undergoing neurosurgical clipping or endovascular coiling of aneurysms. In addition, we compared the incidence of symptomatic vasospasm in patients by neurosurgical clipping or endovascular coiling.Methods Data were analyzed from972patients with intracranial aneurysms enrolled in Union hospital and Wuhan general hospital of Guangzhou command, PLA. Multivariable logistic regression with backwards selection was derived to define independent predictors of symptomatic vasospasm.Results In multivariable analysis, symptomatic vasospasm was not associated with the history of hypertension, smoking and diabetes mellitus, aneurysmal size and number, the use of dehydrant and low dosage nimotop. Factors that contributed most to variation in symptomatic vasospasm, in descending order of importance, were fisher grade of computed tomography (CT) scan, aneurismal location, Hunt-Hess scale on admission, rupture times, the operating day from first rupture, increasing age, treatment modality and male gender.Conclusions Although most prognostic factors for symptomatic vasospasm after subarachnoid hemorrhage (SAH) are present on admission and already fixed; for suitable patients, endovascular coiling and early intervention are recommended.