Naoluotong Clinical And Experimental Study On Treatment Of Vascular Dementia In The Elderly

Through the study on the etiology and pathogenesis as well as the pathological progression of the vascular dementia, It's basis is the "deficiency of kidney essence and exhaustion of Marrow" . it is understood that its main pathogenesis is "obstruction of the brain due to phlegm and blood stasis" Under the guideline of the ideas of "Free flow of qi and blood is important for the brain" and "The brain will not be clear if phlegm is not resolved, and the mind cannot dominate itself if the blood stasis is not removed" deficiency of kidney" essence and the deficiency of nourishing the brain and marrow the basic principle of "resolving phlegm and removing blood stasis" and "nourishing kidney essence and benefitthe "sea"of marrow" is set up for vascular dementia. According to the pathologic characteristics of the vascular dementia, the patent herbal medicine "Tea for Freeing the Brain Vessels from Obstruction" (Nao Luo Tong Chong Ji) has been developed under the principle to resolve phlegm and remove blood stasis and "nourishing kidney essence and benefitthe "sea" of marrow" It is applied for treating patients of vascular dementia. Observation over 106 cases shows that the medicine has an obvious effect in improving the clinical symptoms and signs of patients, reducing the viscosity of blood, and improving the biochemical criteria of blood. The rate of the remarkable results reaches 72. 64%, and the total effectiveness amounts to 89.78%. "Tea for Freeing the Brain Vessels from Obstruction" (Nao Luo Tong Chong Ji) used for mice made dementia with scopolamine is noticed to have an obvious effect in improving the memory and spatial resolution of mice received the treatment. Experiment with the medicine on rats of vascular dementia shows that it has the effect in enhancing the activity of SOD of the body, inhibiting the lipid peroxidation, and improving the blood supply in the brain.