Engineering Peptide Anti-staphylococcus Aureus Is Mrsa Infections In Burned Rats

Objective To study the antimicrobial activity of Ph-SA (Pheromonicin-Stapfiylococcus aureus)on wound infections after deep partial-thickness burns in rat.Methods Sixty Sprague-Dawley(SD) rats with deep partial-thickness burns were randomly divided into 3 groups—-Ph-SA group, vancomycin group and control group—-with twenty ones in each. The rats of Ph-SA group were treated externally once with Ph-SA, with the rats of vancomycin group treated with vancomycin, in contrast with the rest ones treated with 0.9% saline solution, respectively. Two pieces of the infection tissues were obteined at the 1st, 3rd, 5th, 7th day, including one blent with 0.9% saline solution, and centrifugate the homogenate to count the bacterials and the other used to compare the...