| Objective: The abnormality of blood pressure especially the influence ofthe hypertension upon people's living quality be more and more big, butthe acupuncture can change the appearance of this kind ofabnormality. Although the influence of the needling upon the body bevarious, always see to is a kind of positive double to adjust a function,then pass to trigger the body oneself proper adjustment system(nerve,endocrine, immune system), and enhance its function to some extent, butindirectly carry out the cure that it defends a disease, strengthenimmunity function and remove second healthy appearance etc. function. Forclarifying needle of this kind of is to the mechanism which regulates aneffect, this item study at ingreat quantities clinical and experimentfoundation up, pass acupuncture pointses, such as the needling differentrats" Auricular concha ", "Quchi" of the blood pressure appearanceand"Neiguan" and"Zusanli"...etc., inquiry into needle to regulatehypertensive rats and it ties the relation of nucleus of solitary tract.Methods: The study was performed on male healthy Sprague-Dawley rats,whose weight ranged from 280-380g, and were anesthetized with urethane.according to brain stereotaxis atlas of rat (Paxinos and Watson,1998), expose the brain tissue of NTS (-11.3～-14.3mm posterior to bregma,0～2.3mm lateral tomidline, and 4～7 mm below dura). The extracellulardischarge signals were recorded with glass microelectrode. Artery cannulaand vein cannula are inserted into carotid artery and jugular respectively,artery cannula is connected with injection syringe and pressure receptor,vein cannula is connected with injection syringe directly. The bloodpressure was inputed to energy transducer; the signal was outputted toPowerLab data-collecting system. Under the same situation, we stimulatedpositions include "Auricular concha","Quchi","Neiguan","Zusanli"by hand acupuncture and observed its effect on discharges of nucleus of solitary tract and the pressure. when the recording was finished,circulateed 20μA direct current to glass microelectrode and importedpontamine sky blue to brain tissue and located the recording place,deleted the data which was out of the place of NTS.Results: 1 Under the condition of normal-blood-pressure, hypertension orhypotension, acupuncture can all significantly increase the firingfrequency of NTS (P＜0.01), yet compare with normal-blood-pressure,whatever it is hypertension or hypotension, the spontaneous backgroundactivity both increased, but it is of no significant difference (P＞0.05).2.. Acupuncturing "Quchi" can not only increase the discharge frequencyof NTS of the normal-blood-pressure rats and hypotension rats(P＜0.05),butalso the hypertension rats (P＜0.01); yet compare withnormal-blood-pressure rats, whatever it is hypertension rats orhypotension rats, the spontaneous background activity both increased, butit is of no significant difference (P＞0.05).3. Acupuncturing "neiguan" can not only increase the dischargefrequency of NTS of the normal-blood-pressure rats and hypertension rats(P＜0.05), but also the hypotension rats (P＜0.01); yet compare withnormal-blood-pressure rats, whatever it is hypertension rats orhypotension rats, the spontaneous background activity both increased, butit is of no significant difference (P＞0.05).4. Acupuncturing "zusanli" can not only increase the dischargefrequency of NTS of the normal-blood-pressure rats and hypertension rats(P＜0.05), but also the hypotension rats (P＜0.01); yet compare withnormal-blood-pressure rats, whatever it is hypertension rats orhypotension rats, the spontaneous background activity both increased, butit is of no significant difference (P＞0.05).5 hcupuncturing "Auricularconcha" can obviously decrease the pressureof the hypertension rats and normal-blood-pressure rats (P＜0.01), buthas not significant effect on the hypotension rats (P＜0.01); yet hypertension rats and normal-blood-pressure rats both have moresignificant depressurization effect than hypotension rats, there is nostatistical difference between hypertension rats andnormal-blood-pressure rats (P＞0.05).6 Acupuncturing "Quchi" can obviously decrease the blood pressure ofthe hypertension rats (P＜0.01) and normal-blood-pressure rats (P＜0.05),and the effect of acupuncture on the former is obviously than that on thelater(P＜0.05), Acupuncturing "Quchi" can slightly made the mean bloodpressure of the hypotension rats increased,yet it is of no significantdifference (P＞0.05).7 Acupuncturing "Neiguan" can obviously increase the mean bloodpressure of the hypotension rats(P＜0.01)and normal-blood-pressure rats(P＜0.05), and the effect of acupuncture on the former is obviously thanthat on the later (P＜0.05), Acupuncturing "neiguan" can slightly madethe mean blood pressure of the hypertension rats de creased,yet it isof no significant difference (P＞0.05).8 Acupuncturing "Zusanli" can obviously decrease the mean bloodpressure of the hypertension rats (P＜0.01), Acupuncturing the samepoint can significantly increase the mean blood pressure of hypotensionrats (P＜0.05), yet Acupuncturing "zusanli" made the mean bloodpressure of normal-blood-pressure rats decreased, yet it has nostatistical significance (P＞0.05).Conclusions:Our research studied the effect of needing "Auricularconcha","Quchi" "Neiguan" and "Zusanli" by hand on the dischargesof NTS and the blood pressure.Our result showed that acupuncturing thefour points above could all effectively activiated the discharges of NTS,especially when needling "Auricular concha",at the same time aupuncrurecould have regulating effect on the blood pressure of the animals. Theregulating effect had relationship with whether activating NTS directlyor indirectly or activating the segmented sympathetic nerve of the cardiovascular system. When the excitability of the vagus nervepredominated, it caused depressurization effect, and when theexcitability of segmented sympathetic predominated, it causedboosting-pressure effect, which could keep a balance status of autonomicnerve under different situation, and educed the nonmalignant two-wayregulating effect. |
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