Efficacy Of Moxibustion With Ginger In Preventing Toxicity Of Chemotherapy And Affect On Quality Of Life On Cancer Patients

As cancer is one of major disease threatening people's health. cancer has become an important mortal factor beyond cardio-cerebrovascular diseases.About 7000 thousand people died from cancer all over the world every year.In our country,1600 thousand new patients being identity annually.Most patients are dignosed at middle or late stage of cancer.About eighty percent patients need to be treated with chemotherapy or radiography.So,chemotherapy was used more and more popular.During the treatment,cancer cells were killed as well as many normal tissue cells.Patient often suffer from restrain in narrow, digestive tract problems such as nausea,vomiting and diarrhea,even some impairment in lung,heart,liver,kidney and nervous system.The quality of life was affected seriously.Some data show that 20%-50%patients suffer from leukocytopenia after chemotherapy or radiography.It is should be faced and resolved.If leukocytopenia can not be controlled immediately, some serious inflammation will occur.Therefore,preventing patients from leukocytopenia is very important.Since cancer is difficulty to be cured, effectiveness is hardly to evaluated by cure rate.So,quality of life become more and more important in evaluating effectiveness of cancer-treating.Some agreement has been formed in oncology.quality of life can react the effectiveness and patient's condition more accuracier than survival rate and fatality rate.Many researches about leukocytopenia has been done.But their main purpose is to treat patients with leukocytopenia after chemotherapy or radiography.At present,clinic reports about preventing toxicity of chemotherapy are few.As for normative designed research is almost blank.Objective:In the my clinic research,the main propose is to observe the efficacy of Moxibustion with ginger used in different frequent in against toxicity and side effects of chemotherapy,and the affect on quality of life of cancer patients.Methods:90 cases with different cancer were randomly divided into daily Moxibustion with ginger group(A),every other day moxibusion with ginger group(B)and control group(C)with 30 cases in each group.Acupoints Dazhui(GM14),Geshu(BL17),Pishu(BL20),Weishu(BL21)and Shenshu(BL23)were used in both treatment groups.14 days make a course.White blood cell,Neutrophil(N),Hemoglobin concentration and platelet count were observed.90 cancer patients completed the KPS and the QLQ-C30 qustinnaire before,during(one week after treatment),and after treatment(two week after treatment),respectively.Before treatment,some baseline factors such as sex,age,cancer type,patient's condition were compared within three groups.The results show that there are no significant different within three groups.The comparability is good.Results:Results show that Moxibustion with ginger can reduce the extent of degree of White blood cell,Hemoglobin concentration,Platelet count,Neutrophil in two treatment groups than that in control group after one week treatment and two weeks treatment(P＜0.05 or P＜0.01).Some research show that the scores of all the subscales of QLQ-C30 were lowest when patients were receiving treatment in the course of chemotherapy.After treatment,either one week or two weeks,the result of Function Scales in QLQ-C30 shows that the scores of Physical Functioning,Emotional Functioning,Social Functioning and Cognitive Functioning are significant different(higher)from that of control group(P＜0.05 or P＜0.01).The score of KPS in both two treatment groups are significant different from that of control group after treatment. Compared with score before treatment,the score of Global Health in both two treatment groups are not significant different from that of control group after treatment(P＞0.05).Moxibustion with ginger can reduce the severity of clinic symptoms such as fatigue,nausea and vomiting,appetite loss,diarrhea significantly in both treatment groups than that in control group after one week treatment and two weeks treatment.Insomnia,pain, dyspnoeaConclusion:After treatment,the levels of WBC,Hb,PLT,Nent of patients in both groups of Moxibustion with ginger were significantly higher than that in control group.After treatment,patients have less side effects in both groups of Moxibustion with ginger and better quality of life than those in control group.Moxibustion with ginger is a good method to prevent side effect and toxicity Of chemotherapy.