Type 2 Diabetes Phlegm-heat Each End Syndromes Of The Distribution And Biology Of Basic Research

According toWorld Health Organization statistics,There is more than 170 million by 2025 which is expected to more than 300 million all over the world with diabetes,diabetes prevalence was 6.3%.China's current annual increase of one million cases of diabetes,of which 95 percent are type 2 diabetes, active prevention and treatment of type 2 diabetes has become a major public health problem in society.The use of effective prevention and treatment of diabetes in Chinese medicine are important academic research mission.Instructor for many years engaged in diabetes clinical and research work,clinical practice and the instructor group study shows that previously Phlegm-heat syndrome are the main type of type 2 diabetes syndrome.The purpose of this study are of the type 2 diabetes Phlegm-heat syndrome explore theoretical,clinical epidemiological surveys and basic research in biology,with a view to clarify the type 2 diabetes Phlegm-heat syndrome distribution and basic biology.1.Theoretical Study of some sort of diabetes etiology and pathogenesis of TCM Syndrome Types with the research literature,provides an overview of diabetes TCM Syndrome-and micro-target the relationship between research, summarized instructor of type 2 diabetes Phlegm-heat syndrome know and treatment experiences.Reached the following conclusion:long-term adverse living habits associated with modern mental stress,physical changes are diabetic it is also an inter-node heat syndromes formed the most important factor.Type 2 diabetes Phlegm-heat syndrome because of its formation have been many food,many sitting paucimobilis,mental tension due.Pathogenesis of type 2 diabetes during the heat can be inter-node co-exist easily with the internal organs is cemented, easily gas consumption and easy to heat,such as blood stasis Phlegm,pathogenic complexity,heat each node can block the gas machine,blood,variable permit proliferation with extensive disease,in view of its extensive disease,the complexity of the characteristics of clinical attach great importance to and actively control type 2 diabetes Phlegm-heat syndrome.2.Part of clinical research using randomized,stratified,cluster sampling method A prospective study of Beijing Xuanwu District,Changping District, and Pinggu District 3 community over the age of 20 community residents to live a long 5465 for diabetes epidemiology and people TCM Syndrome Study investigate. Draw the following conclusions:Type 2 Diabetes and Diabetes past differences, non-typical "one little more than three" symptoms of obese patients with type 2 diabetes as the main body of Phlegm-heat syndrome is type 2 diabetes,one of the main type.A correct understanding of its role and status,for patients with type 2 diabetes control the disease of great significance.3.Part of basic research to abnormal metabolic status as the breakthrough point,from anthropometry,blood metabolism study,the three levels of endocrine factors such as type 2 diabetes study of Phlegm-heat syndrome each end of the biological basis of evidence,to draw the following conclusions:Phlegm-heat syndrome group resistin secretion was significantly higher,with the hot-Yin deficiency syndrome group permit difference between groups was significant, suggesting that resistin could be used as evidence to distinguish between Phlegm-heat,the hot-Yin deficiency Syndrome target different;adiponectin the level of pigment-type group than in the two permits a significant reduction in the control group,leptin,IL-6 level of the two syndrome group than in the control group significantly increased.E-selectin,TNF-α,GLP-1 level of each node Phlegm-heat syndrome group than in the hot Yin deficiency syndrome group and the control group no significant difference,but the trend has increased; body mass index,waist-hip ratio,sugar metabolism in the target fasting blood glucose,glycosylated hemoglobin insulin,C-peptide levels,lipid metabolism in the target cholesterol,triglyceride,low-density lipoprotein,very low density lipoprotein,three renal urinary albumin excretion rate in urine,sugar protein andβ2-microglobulin,blood pressure,hematocrit,fibrinogen, C-reactive protein in the target Phlegm-heat syndrome group than the hot-Yin deficiency syndrome group no significant difference between groups,but there is increase or decrease the Change trend,suggesting that there are differences between type 2 diabetes Phlegm-heat syndrom and the hot-Yin deficiency syndrome,and evidence of the possible differences need further study.This study has two innovations:1.To carry out a prospective type 2 diabetes mellitus syndrom epidemiological survey distribution,evidence for Type 2 diabetes to provide an objective study of ideas and methods,data confirmed the evidence that type 2 diabetes Phlegm-heat syndrome was one of the main syndrom. 2.Combined withmodern medical research progress in a number of target selection, type 2 diabetes Phlegm-heat syndrome evidence for the basic biology of many ways to explore multi-level active.