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Studies On Constituents And Quality Control Of Bupleurum And Constituents Of Veratrum Schindleri Loes.f.

Posted on:2011-02-03Degree:DoctorType:Dissertation
Country:ChinaCandidate:H Q HuangFull Text:PDF
GTID:1114360308981678Subject:Medicinal chemistry
Abstract/Summary:PDF Full Text Request
In this study, attempts have been made to isolate and define the bioactive and toxic constituents from plants of Bupleurum chinense and B. longiradiatum, to explore chemical components in Bupleurum and clarify the bioactive and toxic material foundation in this genue. From the two plants, 34 compounds in total have been obtained, including 10 new compounds. Furthermore, different kinds of analical methods, including qualitative and quantitative analysis and chemical fingerprint method, have been developed for the comprehensive quality control of Bupleurum, which will ensure the the safety and effective of Chaihu in clinical usage. In addition, another plant, Veratrum schindleri, was also investigated for chemical constituents. From the entire parts of this plant, 36 compounds were isolated and identified including 2 new compounds and 34 compounds isolated from the plant for the first time.
Keywords/Search Tags:Bupleurum, chemical component, toxic constituents, saikosaponins, polyacetylenes, quality control, qualitative analysis, quantitatively analysis, fingerprint, Veratrum schindleri
PDF Full Text Request
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