Impact Of Multivessel Lesions On Short-term Prognosis In Patients With Acute Myocardial Infarction

Background and ObjectsNowadays, percutaneous coronary intervention is the main treatment of acute myocardial infarction, and can improve the outcomes. Infarct-related artery (IRA) revascularization is recommend. While non-infarct-related artery (NIRA) is not the crime blood vessels, whether combined with NIRA will increase mortality or the incidence of adverse events? The long-term prognosis of multivessel lesions has mostly been considered in prior studies, and this paper will investigate the short-term prognosis of the AMI patients with multivessel lesions.Subjects and MethodsWe studied453patients who underwent successful PCI and follow-up of3months from January2009to November2011with a diagnosis of AMI at the Department of Cardiology of Sir Run Run Shaw hospital affiliated to zhejiang university school of medicine. We collect the clinical data and follow-up results. According to coronary angiography, we divided the patients into single-vessel (n=141) and multivessel (n=312), and multivessel is divided into double-(n=145) and triple-vessel (n=167).ResultsIn the follow-up to the453AMI patients who successfully underwent PCI, rates of single-, double-and triple-vessel disease were31.1%,32.0%,36.9%; The3-month cardiac mortality of each groups were3.5%,3.4%,4.2%, no difference; non-fatal myocardial infarction occurred in2cases (0.4%); cerebral infarction occurred in6cases (1.3%); revascularization occurred in9cases (2.0%). Major adverse cerebral cardiovascular event rates were4.3%,7.6%,9.6%, no difference; There was no significant difference of event-free survival among three groups.ConclusionsPatients with triple-vessel disease were older, had lower left ventricular ejection fraction, higher serum creatinine, lower creatinine clearance rate, and more hypertension, diabetes and cerebral infarction; There was no significant difference of the short-term prognosis between single-vessel and multivessel disease.