| Purpose: 1 Based on the "Liver and Kidney Theory",this study explores the menstrual disease caused by emotion on the basis of ancient Chinese medicine literature and demonstrates the relationship between “liver stagnation and kidney deficiency” and menstruation caused by emotional irregularities.2 Evaluates the clinical efficacy and application value of “Zheng Ji Diao Qi Therapy” treatment for menstrual irregularity caused by emotional factors and demonstrates the evolution of irregular menstruation.Material and method: 1.Through the literature search of traditional Chinese medicine,study the origin of the "liver and kidney theory";the homologous of liver and kidney is closely corelated with the blood source of menstrual;etiology and pathogenesis of the irregular menstruation caused by emotion;syndrome differentiation of irregular menstruation caused by emotion;based the treatment of menstruation from the liver and kidney theory.2.Clinical study on “Zheng Ji Diao Qi” therapy treatment of menstrual irregularity caused by emotional factors.Based on 135 cases with "liver stagnation and kidney deficiency" of irregular menstrual,divided into the following groups: “Zheng Ji Diao Qi” therapy with Chinese Medicine treatment as group A with 35 cases,Chinese Medicine only treatment as group B with 33 cases,“Zheng Ji Diao Qi” therapy with Body Needle acupuncture treatment as group C with 34 cases,and Body Needle acupuncture only treatment as group D with 33 cases.“Zheng Ji Diao Qi” therapy uses “cang gui tan xue” relieve method by focusing on the spinal “Jiaji”,“Qi” regulation by using “Ping Ci Tou Ci” needling method,and in additional with Massage “Zheng ji” methods.Chinese Medicine “Shu Gan Yi Shen” Formula base: "Sheng Mai Ya" 40 g,"Tu Si Zi" 15 g,"Gou QI Zi" 10 g,"Nv Zhen Zi" 15 g,"Xian Ling Pi" 6g,"Chai Hu" 6g,"Dang Gui" 12 g,"Bai Shao" 15 g,"Shen Qu" 10 g,"Sheng Shan Zha" 15 g.Body needling acupoints: “Shan zhong”,“gan Shu”,“shen Shu”,“guan yuan”,“zu san li”,“tai xi”,“tai chong”,“san yin jiao”,“a shi xue” and other acupoints.Selective Acupoint: “ā shì xué”;toward patient’s abdominal palpation,pressing liver meridian,feeling lower abdomen and peritoneal tension to select corresponding reaction point as acupoint.Based on HAMD depression scale,SF-36 life quality scale,along with clinical observation of emotional depression status and life quality as guideline;applies visual analogue scale VAS method to observe pain indicators;laboratory examination of blood rheology indicators,Determination of prostaglandins by enzyme-linked immunosorbent assay(ELISA)and the use of automatic biochemical analyzer to determine the serum immunoglobulin Ig G,Ig A,Ig M levels;monitoring the correlation of age,the course and duration of disease and treatment effectiveness.Results: 1.Based on the origin of the “liver and kidney theory”,it is considered that liver is the main organ for blood filtering,and that kidney is the main source and closely related to menstruation,liver and kidney are homologous,the yin and yang are complementary,the release and sealed to work together.Emotional depression is the source of menstrual disease mainly caused by anger,qi stagnation and blood stasis are the source of pathogenesis,qi and phlegm stagnation are pathological products,“Xiang Huo Wang Dong”,sealing stagnation is the key and blood deficiency is the source of the pathogenesis.Irregular menstruation caused by emotional depression can be divided into five major liver stagnation types: qi stagnation,spleen deficiency,phlegm stagnation,kidney deficiency,“yin” deficiency of liver and kidney,and the primary focus on liver stagnation and kidney deficiency.2.Clinical study on the treatment of irregular menstruation caused by emotional depression2.1.Through statistical analytic observation of the overall before and after treatment efficacy and effective rate of each groups as follow: “Zheng Ji Diao Qi” therapy with Chinese Medicine treatment(group A)was 97.14%,Chinese Medicine only treatment(group B)was 87.88%,there was a significant difference shown in Ridit test,U=2.2002,P<0.05.“Zheng Ji Diao Qi” therapy with Body Needle acupuncture treatment(group C)was 88.24%,and Body Needle acupuncture only treatment(group D)was 66.67%,there was a significant difference shown in Ridit test,U=2.0594,P<0.05.In comparison between “Zheng Ji Diao Qi” therapy with Chinese Medicine treatment(group A)and “Zheng Ji Diao Qi” therapy with Body Needle acupuncture treatment(group C),there was a significant difference shown in Ridit test,U=2.2848,P<0.05.2.2.Through statistical analytic comparison by using the HAMD depression scale for after treatment in each treatment groups,there were a very significant differences in data comparison between the following: group A and group B with t=5.652,P<0.01,Group C and group D compared with t=2.793,P<0.01.There were also significant differences in data comparison between the following: group A and group C with t=5.30,both P<0.05,and the 3 months treatment follow-up was statistical showing both at P<0.05.2.3 Evaluate the quality of life index for each treatment groups based on physiology,physical function,physical pain,physical condition,energy,social ability,emotional function,and mental health;with initial post-treatment and 3 months post-treatment follow-up by statistically data process analytic and score dimensions data comparison in SF-36 quality of life scale;the results were significant and very different with P<0.05,and P<0.01.2.4 In the statistically data process analytic and score dimensions data comparison evaluation based on somatization,coercion,interpersonal relationship,depression,anxiety,hostility,etc,with SCL-90 SCL Symptom Checklist scale as the primary efficacy indicators;the results were significant and very different with P<0.05,or P<0.01.2.5 Scores comparison of before and after treatment for dysmenorrhea in each treatment groupsIn the statistically data process score comparison with P<0.05,or P<0.01 for dysmenorrhea in each treatment groups to compared before and after treatment;after treatment data comparison between groups as follow: group A and group B with t=2.03,p<0.05;group C and group D with t=1.85,P>0.05;group A and group C with t=1.48,P>0.05.2.6 Comparison of Prostaglandin levels for before and after treatment in each treatment groupsIn the statistically data process and comparison with P<0.05,or P<0.01 for prostaglandin levels in each treatment groups to compared before and after treatment;after treatment data comparison between groups as follow: group A and group B with t=2.36,P<0.05;group C and group D with t=2.05,P<0.05;Group A and group C with t=1.98,both at P<0.05.It shows significant difference.2.7 Comparison of blood rheology indexes for before and after treatment in each treatment groupsIn the statistically data process and comparison of blood rheology indexes based on the blood viscosity,whole blood viscosity,platelet adhesion rate,and hematocrit for before and after treatment in each treatment group;Through blood viscosity statistical analytic comparison of before and after treatment for each treatment groups,group A t=6.76,P<0.01,group B t = 2.08,P<0.05,group C t = 2.43,P< 0.05,group D t = 2.01,P<0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B with t=2.86,P<0.01,group C and group D with t=1.07,P>0.05,group A and group C with U=1.98,P<0.05.Through whole blood viscosity statistical analytic comparison of before and after treatment for each treatment groups,group A t=7.56,P<0.01,group B t=2.04,P<0.05,group C t=2.89,P<0.01,group D t=2.05,P<0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B with t=2.76,P<0.01;group C and group D with t=1.08,P>0.05,group A and group C with U=2.05,P<0.05.Through platelet adhesion rate statistical analytic comparison of before and after treatment for each treatment groups,Group A was t=6.86,P<0.01,group B was t=2.44,P<0.05,group C was t=2.87,P<0.01,group D was t=2.15,P<0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B with t=2.86,P<0.01;group C and group D with t=1.48,P>0.05,group A and group C for U=2.15,P<0.05.Through hematocrit statistical analytic comparison of before and after treatment for each treatment groups,group A was t=9.87,P<0.01,group B was t=2.24,P<0.05,group C was t=4.16,P<0.01,group D was t=2.25,P<0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B with t=4.83,P<0.01,group C and group D with t=1.68,P>0.05,group A and group C with U=4.15,P<0.01.2.8 Comparison of serum immunoglobulin levels for before and after treatment in each treatment groupsThe levels of serum immunoglobulin were compared for before and after treatment in each treatment groups;through Ig G statistical analytic comparison of before and after treatment for each treatment groups,group A was t=4.04,P<0.01,group B was t=2.12,P<0.05,group C was t=1.99,P<0.05,group D t=1.52,P>0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B with t=2.31,P<0.01,group C and group D with t=0.41,P>0.05,group A and group C with U=2.10,P<0.05.Through Ig A statistical analytic comparison of before and after treatment for each treatment groups,group A was t=3.45,P<0.01,group B was t=1.99,P<0.05,group C was t=2.02,P<0.05,group D was t=1.62,P>0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B were compared with t=2.42,P<0.01,group C and group D with t=0.42,P>0.05,group A and group C with U=2.01,P<0.05.Through Ig M statistical analytic comparison of before and after treatment for each treatment groups,Group A was t=4.18,p<0.01,group B was t=2.04,P<0.05,group C was t=2.22,P<0.05,group D was t=1.73,P>0.05.The post-treatment data shows there was significant difference in data comparison between groups: group A and group B were compared with t=2.12,P<0.01;group C was compared with group D for t=0.82,P>0.05,group A and group C for U=2.05,P<0.05.2.9 Age,course of disease,condition and treatment efficacy relationIn statistic data process and comparison between the relation of age and treatment efficiency for the post-treatment of “Zheng Ji Diao Qi” therapy with Chinese Medicine treatment in group A,the result showed very significant difference with U=9.4772,P<0.01.In statistic data process and comparison between the relation of age and treatment efficiency for the before and after treatment of “Zheng Ji Diao Qi” therapy with Body Needle acupuncture treatment in group C,the result showed very significant difference with U=13.6925,P<0.01.In statistic data process and comparison between course of disease and treatment efficiency relation for the post-treatment of “Zheng Ji Diao Qi” therapy with Chinese Medicine treatment in group A,the result showed very significant difference with U=9.0194,P<0.01.In statistic data process and comparison between the relation of between course of disease and treatment efficiency relation for post-treatment of “Zheng Ji Diao Qi” therapy with Body Needle acupuncture treatment in group C,the result showed very significant difference with U=3.3334,P<0.01.In statistic data process and comparison between the disease condition and treatment efficiency relation for the post-treatment of “Zheng Ji Diao Qi” therapy with Chinese Medicine treatment in group A,the result showed very significant difference with U=9.0194,P<0.01.In statistic data process and comparison between the relation of between the disease condition and treatment efficiency relation for post-treatment of “Zheng Ji Diao Qi” therapy with Body Needle acupuncture treatment in group C,the result showed very significant difference with U=3.4010,P<0.01.Conclusion 1.Based on the research in ancient Chinese medicine literature shows that menstrual irregularity caused by emotion has close relation to liver and kidney,and liver stagnation and kidney deficiency is the main syndrome.2 “Zheng Ji Tiao Qi” therapy can effectively improve the clinical efficiency of irregular menstruation caused by treatment emotions.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.3 “Zheng Ji Tiao Qi” therapy can effectively improve the depression state caused by emotional irregular menstruation.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.4 “Zheng Ji Tiao Qi” therapy can effectively improve the quality of life caused by emotional irregular menstruation.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.5 “Zheng Ji Tiao Qi” therapy can effectively improve the anterior and posterior dysmenorrhea caused by emotional irregularities.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.6 “Zheng Ji Tiao Qi” therapy can effectively improve the prostaglandin level caused by emotional irregular menstruation.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.7 “Zheng Ji Tiao Qi” therapy can effectively improve the blood rheology index caused by emotional irregular menstruation.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.8 “Zheng Ji Tiao Qi” therapy can effectively improve the serum immunoglobulin level caused by emotional irregular menstruation.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C.9“Zheng Ji Tiao Qi” therapy is effective in treating menstrual irregularity caused by emotional sensation.The lighter the age,the better the curative effect.“Zheng Ji Tiao Qi” therapy with Chinese Medicine treatment in group A is better than “Zheng Ji Diao Qi” therapy with body needle acupuncture treatment in group C. |
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