Polycyclic aromatic hydrocarbons (PAH) are ubiquitous organic pollutants in ambient air. 2-4 Ring PAH exist, in general, in the gas phase and can react to form a variety of atmospheric reaction products. These reaction products, depending on their formation yields and atmospheric stability, may be present in sufficiently high concentrations to be of equal or greater mutagenic potency than their parent compounds. Although many studies have investigated the mutagenicity of ambient air components in microbial systems, few investigators have looked at the genotoxicity of these compounds in human cell lines. This study investigated in detail the atmospheric reaction products of naphthalene due to its reactions with OH and NO... |