Effectiveness of delta-aminolevulinic acid-induced protoporphyrin as a photosensitizer for photodynamic therapy in vivo and in vitro

hotodynamic therapy (PDT) consists of the systemic administration of a photosensitizer and subsequent exposure of malignant lesions to visible light. Absorption of photon energy by the photosensitizer in tumors induces an oxygen-dependent photochemical reaction that most probably results in the generation of toxic singlet oxygen (;We examined the effectiveness of...