| I investigated whether the nuclear import of karyophilic proteins and various U snRNPs occurs by a common kinetic pathway. When injected into Xenopus oocytes, saturating concentrations of P(Lys)-BSA reduce the import rate of both (;The import of U6 snRNA, which lacks a m;The import of most Xenopus oocyte nuclear proteins is directed by nuclear localization signals (NLSs) from a single family whose members are related to the archetypal NLS of SV40 large T-antigen. The transport of microinjected (;Most (... |
