Modification of the calcium(II) release system of skeletal muscle sarcoplasmic reticulum vesicles via sulfhydryl oxidation and tryptic proteolysis

The sarcoplasmic reticulum (SR) is an intracellular membrane system which regulates the concentration of Ca;Isotopic and spectrophotometric assays show that micromolar concentrations of heavy metal ions (particularly Ag;Modification of the SR with the proteolytic enzyme trypsin enhances the rate of Ca...