| Objective: To establish the macroscopic quantitative diagnostic standard of liver fire flaming upward syndrome of hypertensive disease and explore a new method of standardization of TCM syndrome differentiation.Methods: Control study of modern literature and clinical retrospective study on distribution rule of TCM syndromes of hypertensive disease were respectively carried first. The macroscopic diagnostic scale of liver fire flaming upward of hypertensive disease was constituted according to literature research, clinical epidemiological investigation and expert consultation.Then, the re1iability, validity and responsiveness of the scale were evaluated. The macroscopic quantitative diagnostic model and standard of liver fire flaming upward of hypertensive disease were established by determining item weights according to epidemiological investigation. Clinical diagnostic experiments were performed on the standard finally.Results: This research revealed that liver fire flaming upward was one of the most common TCM syndromes of hypertensive disease.The diagnostic scale of liver fire flaming upward of hypertensive disease was compiled and proved to have good re1iability, validity and responsiveness. The quantitative diagnostic standard of liver fire flaming upward of hypertensive disease was established, whose lowest critical value was 230. Clinical diagnostic experiment showed that it had high sensitivity, specificity, accuracy and positive likelihood ratio.Conclusion: The diagnostic scale of liver fire flaming upward of hypertensive disease established through literature research, clinical epidemiological investigation, scale compilation, statistical analysis and clinical verification has good feasibility, accuracy and clinical practical value. The results of this research will offer standardized scale for further research of liver fire flaming upward of hypertensive disease and provide ideas and methods for standardization study on other syndromes. |
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