Study On Recycling And Separation Of Antibiotic From Pharmaceutical Wastewater By Adopting Nanofiltration Membranes

A study of Lincomycin recycling and separation from fermentation wastewater by adopting Nanofiitration (abbre. NF) membranes is presented in this paper. Several types of flat and spiral NF membranes are used under dynamic operation conditions, though which the optimal membranes and operation conditions are determined. In addition, several different technological processes are experimented, the results of the experiments are analyzed and compared too.The evaluate criterions on membrane properties are mainly the water flux , CODCr retention rate, iincomycin retention rate and the multiplier of water flux and lincomycin retention rate. The concentration of lincomycin demanded in reuse is 2000 mg/i, and the recycling rate is over 90%.As known from the experiments on eight types of fiat NF membranesDL?NF membrane (made by Daiian Institution of Chemical Physics) has the optimal properties such as the higher water flux , higher retention of CODcr and iincomycin , the most steady properties among several domestic NF membranes. Moreover, the cost of this kind of NF membrane is less than that of exotic NF membranes.MPF?4 NF membrane (made by MPW corporation . Israel ) is the optimal NF membrane among the several exotic membranes, which has the highest retention of CODCr and lincomycin and the most steady properties. In addition , it is the unique solvent?resistant NF membrane.The DL NF membrane and MPF?4 NF membrane are adopted as the membranes used in semindustrial pilotcale study or in the industrial process due to their excellent properties.Through the experiments on different pressure and feed flux , the optimal operation pressure of those two types of NF membrane is ascertained: DL NF membrane optimal pressure is 2.0 MPa, the MPF?4 NF membrane optimal pressure is 3. 0 MPa, the suitable feed flux ranges from 8 to 12 1/mm.After the dynamic experiments of spiral DLF2?0 NF membrane andMPS--44 NF membrane, resu1 ts indicate that the concentrat ion of 1 incomyci ncan reach 2000mg/1 or higher when using the norma1 process eff1uent asfeed and concentrating the wastewater about 10~20 times, which can reachthe demand of reuse. The concentration time is re1ated with the membrane'swater f1ux l membrane's area, and feed concentration.Three series processes are designed that DL--NF,--30 NF membrane andMPS--44 NF membrane are contacted to concentrate the wastewater, thesecond series process (MPS--44 NF membrane is adopted as concentrationgrade to treat the primi tive wastewater, and DL--NF,--30 NF membrane is usedas follow--up concentration grade to treat the water flux of MPS--44 NFmembrane) is more beneficial when compared wi th other series processes,which can not on1y reach the reuse demand but also the recyc1ing rateis over 90%. DL--NF,--30 NF membrane is fit for treating 1ower concentrationwastewater and can be used as preconcentration grade or fo11ow--upconcentrat ion grade in different techno1ogica1 processes. MPS--44 NFmembrane's properties are very steady ) and can be used as concentrationgrade to treat the 1 incomycin ferment waste water.NF membrane used in treatment of 1incomycin wastewater can not on1ybenefit environment but a1so benefit the economy and society. 1t wou1dbe prospective that applying NF membrane in the treatment of antibioticwas t ewat er.