The Direct Oxidative Amidation Of The Aldehydes And Amines And Oxidation Of The Benzyl Halide

The dissertation consists of three chapters. In the first chapter, the application of hypervalent iodine(III) reagent and ionic liquids to organic synthesis is briefly reviewed. The second one is about the direct oxidative formation of amides from aldehydes and amines using a hypervalent iodine(III) reagent or an ion-supported hypervalent iodine(III) reagent. In the last one, selective oxidation of halide into aldehydes and ketones by ion supported N-oxide reagent was studied.There are two parts in the chapter one. Part one, the new development of hypervalent iodine reagent is briefly instructed and the application of hypervalent iodine(III) reagent: selective oxidation; activation of the C-H bonds; activation of the alkenes and alkynes; oxidative rearrangements and fragmentations are described. Part two: the application of ionic liquids is instructed.In chapter two, a metal-free direct oxidative formation of amides from aldehydes and amines using a hypervalent iodine(III) reagent or an ion-supported hypervalent iodine(III) reagent as a recyclable oxidant at mild conditions was studied. The easy availability of the starting materials, the simplicity and the high efficiency of the reaction procedure, the recoverable and recyclable properties of the oxidants, as well as the mild reaction conditions should render this protocol attractive to synthetic chemists.In chapter three, the synthesis of an ion supported N-oxide reagent and selective oxidation of halide into aldehydes and ketones by ion supported N-oxide are described. This work is in progress.