Preparation And Performance Of Functional Polymer Materials

Functional polymer materials were widely used in medicine and environment protection fields. With the constant development of functional polymer materials on biocompatibility and environmental friendliness, a still higher demand on the synthetic raw materials and methods was shown. In this thesis, works focus on the application of chitosan and methacrylate on drug controlled release and water pollution respectively.Radiation polymerization has special advantages for the functional polymer materials preparation, due to not using noxious chemicals such as crosslinkers and initiators, low energy consumption, light pollution and environmental friendliness. Amphiphilic O-maleoyl-N-phthaloyl-chitosan-g-polyvinyl pyrrolidone (MPCS-g-PVP) was prepared byγ-ray. The properties of self-assembles, drug loading and release behavior were studied. Result showed MPCS-g-PVP aggregates into micelles and loads oil-soluble drug indomethacin(IDM) well in aqueous solutions. The mean diameter of micelles increases from 265nm to 380 nm after loading IDM. The in vitro release of IDM from the drug-polymer micelles was significantly slower compared to pure IDM. All these showed MPCS-g-PVP a promising application prospect for drug delivery system.The optimal treatment of infectious fractures with bone defects is one-stage embedding of bone-grafting materials. An antimicrobial osteogenic bioceramic combined with chitosan, ceftriaxone sodium, bone morphogenetic proteins (BMP) and calcium phosphate cement(CPC) was synthesized and studied. Results showed the white blood cell(WBC) number and tissue section showed lighter inflammatory response and better osteogenesis of treatment group than control group during contaminated bone defect experiment. Excellent antimicrobial osteogenic effect and simple preparation identified it as a promising embedded material for contaminated bone defect.More and more interest has been paid to super oil - absorbable resins (SOAR) due to the aggravation of oil pollution. SOAR was prepared through the emulsion polymerization of lauryl methacrylate initiated byγ-ray. Oil absorption and keeping performances of the polymer was studied through weights. Results showed the maximal saturated kerosene ratio of Polylauryl methacrylate (PLMA) is 18.1, while mechanical oil keeping ratio is 93.7%. PLMA initiated byγ-ray shows good oil absorbance and keeping performance, these make PLMA an amazing SOAR.