Study On The New Synthesis Technology And Its Kinetics Research Of 2, 6-Dimethypiperazine

2,6-dimethylpiperazine is all important fine chemicals and pharmaceutical intermediate. It can be used in the synthesis of pharmaceuticals, pesticides, dyestuffs, surfactants and etc. In this study, we seleted the process route for technical grade 1,2-propanediamine to synthesize 2,6-dimethypiperazine in one-step by gas-solid phase catalytic at normal pressure, the synthetic route of 2,6-dimethyl-piperazine's conversion and selectivity are higher. We impregnated the powderyγ-Al2O3 carrier to load three kinds of metal components Cu,Cr,Fe to improved the catalyst. Optimized the preparing process of catalyst and then determined the optimum preparing condition of catalyst:impregnated for 48 hours in the mix solution of 1.0mol/LCu2+/0.5mol/LCr2+/0.5mol/LFe3+, diried for 3 hours at 130℃, baked for 5 hours at 400℃, then reduction for 3 hours with hydrogen at 320℃. Through single-factor and orthogonal experiments, the influence factors about the synthetic process were researched, the optimum process conditions of preparing 2,6-dimethypiperazine were determined:the concentration of raw material 45%(mass), the reaction temperature is 330℃,and the airspeed 510.64hr-1.Under these process conditions, the conversition of 1,2-propanediamine is 98.35%, the yield of 2,6-dimethypiperazine achieved 88.47%. On the basis of the certain best process conditions and parameters, concluded that the reaction process of macrokinetics models at 300℃-340℃after repeated tests, under the conditions of 2,6-dimethypiperazine as generated production, and the following was macrokinetics equation. The macrokinetics models provides a theoretical base and an experimental foundation for the pilot magnification and the industrialization about 2,6-dimethypiperazine.