Research On Extraction Of Alkaloid From Vietnamese Sophora Root With Liquid Membranes

Liquid membrane extraction is a sample pre-dealt technique which has developed in 1960s, It facilitates extraction without the mixing of two phases, thus eliminating emulsion formation and the need for high solvent usage.The attractive features of transport through membranes are their high selectivity and the simultaneous separation and preconcentration of elements, their simplicity, low operational costs, low energy consumption, and the fact that they can be used for a broad spectrum of elements by carefully selecting the carrier, it has becam widely used in medicine, biology, chemistry, biotechnology and water treatment.In this paper, liquid membrane extraction was employed for analyzing matrine.The influencing factors such as the thickness of membrane liquid solvents, the pH value of the acceptor, the extraction temperature and extraction time were investigated.And then, Vietnamese Sophora Root was pre-dealt. The result shows that the lower pH of the accepter can be in favor of reception of the analyte, that organic liquid which is thiner can achieve higher extraction yields, the extraction efficiency increased with the time of up to 100% at room tempeature.In the pre-dealt process of matrine, trichloromethane was selected as the organic membrane liquid.Bulk liquid membrane and supported liquid membrane extraction devices were employed respectively and the former has better stability,however,the extraction efficiency is smaller than supported liquid membrane extraction,because the small contact area per unit volume,With the condition of phosphate buffer solution (pH=1)as accepter, matrine of Sophora Root was pre-dealt.The extracting time last 1 hours and the amount of extracted matrine get to 58.31%.Utilizing upported liquid membrane extraction system, the transferred distance of matrine extended, however, due to the high solubility of trichloromethane which was used as membrane liquid, we can still get high extraction efficiency.In the process of separating alkaloids, supported liquid membrane extraction devices can offer better stability. So we can use volatile organic solvents as membrane liquid to maintain higher efficiency of extraction.Compared with the traditional pre-dealt methods of matrine, membrane extraction technique has many advantages such as simple and quick steps and less consumption of organic solvents, etc.It can avoid the pollution caused by using substantive organic solvents in liquid-liquid extraction process.