Studies On N-heterocyclic Carbene-catalyzed Oxidative Esterification Of Aldehydes With Alcohols Or Phenols And Rongalite -pro Moted Synthesis Of Diarylsulfide

Carboxylic acid ester derivatives and diarylsulfide are important organic intermediates in the field of organic synthesis, pharmaceuticals and polymers and can be found in many biological or pharmaceutical molecules. This thesis consisted of two parts. The first one is focused on N-Heterocyclic carbene-catalyzed oxidative esterification of aldehydes with alcohols or phenols. The second is focused on Rongalite(?)- promoted the reaction of diaryldisulfide with nitroarene for the synthesis of diarylsulfide.In part one, studies on the oxidative esterification of aldehydes with alcohols or phenols and the reactions with N-heterocyclic carbenes as organocatalyst were reviewed. Then, N-heterocyclic carbene-catalyzed oxidative esterification of aldehydes with alcohols and phenols was studied. The remarkable advantages of the reaction are simple operation, metal-free catalyst and mild reaction conditions, which provided an efficient simple and direct method for the synthesis of aryl benzoate derivatives.In part two, Rongalite(?)-promoted the reation of diaryldisulfide with nitroarene for the synthesis of diarylsulfide was studied. The advantages of the reaction are the use of odorless diaryldisulfide, metal-free catalysis, mild reaction conditions and high chemselectivity.