| 1. ObjectiveTo confirm the effects of different treatment courses on the duration of clinical efficacy and sign of patients through treating allergic rhinitis with acupuncture for 4 weeks and 8 weeks.2. MethodA total of 63 allergic rhinitis patients received special outpatient consultation in the Guang’anmen Hospital of Chinese Academy of Chinese Medical Sciences from Jul.2012 to Aug. 2014 and conformed to the inclusion criteria were selected as subjects of this study. In this experiment,1 cases were excluded,2 cases of loss, the actual completion of 60 cases. All the patients, including 27 males and 33 females with an age range of 15-67 years and an average age of 42.8±13.0 years, were definitely diagnosed as perennial allergic rhinitis by otolaryngologists. Inclusion criteria:meet the diagnostic criteria of allergic rhinitis; aged 15-70 years; with a disease course at least 1 year; capable of expressing personal will properly; willing to participate in this study, comply with medical instructions; cooperate with treatments and sign the ICE This study also set exclusion criteria and elimination criteria. Sixty patients with allergic rhinitis were divided into the 4-week group (treated for 4 weeks) and the 8-week group (treated for 8 weeks) for acupuncture treatment according to registration order. The scores of rhinitis symptoms, VAS scores of the overall and classified nasal symptoms, VAS score of rhinitis severity, scores of nasal signs, and mucociliary transport time of all the patients before and after treatment were recorded. Higher scores represent more severe associated symptoms or worse local signs. The scoring of nasal symptoms and record of mucociliary transport time was completed by an otolaryngologist. All the patients were scored by the same otolaryngologist who was not involved in the treatment process. Follow-ups were conducted once in the 3rd month and once in the 6th month after the treatment for each of the patients above, and the content of follow-ups was scoring of rhinitis symptoms and overall nasal symptoms.3. ResultScores of nasal symptoms and signs:the scores of nasal symptoms and signs of patients in both groups after treatment decreased significantly from that before treatment (P<0.01), and the scoring difference of nasal symptoms and signs of patients between the two groups after treatment presented no significance (P>0.01). Effects after treatment:there were 9 (30%) significantly effective cases and 15 (50%) effective cases in the 4-week group, and the effective rate was 80%; there were 3 (10%) significantly effective cases and 18 (60%) effective cases in the 8-week group, and the effective rate was 70%. The effects after treatment presented no significant difference (P>0.01) between the two groups of patients. Color changes of nasal mucosa:the color changes of nasal mucosa after treatment in both groups of patients presented significant difference from those before treatment (P<0.01), and the color changes of nasal mucosa after 8-week treatment presented no significant difference from those after 4-week treatment (P>0.01). Mucociliary transport time:the reduced mucociliary transport time after treatment was significantly different from that before treatment (P<0.01). Comparison of VAS scores for the overall and classified nasal symptoms:the VAS scores for the overall and classified nasal symptoms in patients of both groups decreased significantly from those before treatment (P<0.01); the VAS scores for the overall and classified nasal symptoms of patients between the two groups after treatment presented no significant difference (P>0.01). VAS scores of rhinitis severity:the VAS scores of rhinitis severity in patients of both groups after treatment decreased significantly from that before treatment (P<0.01); the scores of nasal symptoms and signs of patients between the two groups after treatment presented no significant difference (P<0.01). Follow-up results:the scores of rhinitis symptoms and overall nasal symptoms in patients of both groups at the 3rd and the 6th month after treatment presented no significant difference from those after treatment (P>0.05);the scores of total nasal symptom in patients of both groups at the 3rd and the 6th month after treatment presented were significantly different (P<0.05); the scores of total nasal symptom in patients between the two groups at the 6th month after treatment presented were significantly different (P<0.05).4. Conclusions1 Treating allergic rhinitis with acupuncture in this study is effective;2 The effect of long duration group was longer than that of the short treatment group;3 The mucociliary transport time is shortened and the mucociliary transport system function of the patients is improved. |
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