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Experimental Study Of KangLaiTe On Inducing Proliferation And Apoptosis In Human Hepatocellular Carcinoma

Posted on:2001-07-02Degree:MasterType:Thesis
Country:ChinaCandidate:G M B Z ( E K O M O B I D Z Full Text:PDF
GTID:2144360002950865Subject:Oncology (General Surgery)
Abstract/Summary:PDF Full Text Request
OBJECTIVE: To study of proliferation apoptosis effect of humanhepatocellular carcinoma cells on induced by kanglaite injection.METHOD: MTT, Immunohistochemical and microscopy methodswere used in 34 cases to observe primary liver cancer treated invitro with Kanglaite injection compared to it's control group.RESULTS:â‘ anglaite can inhibit hepatocellular carcinoma cellproliferation up to 30%. â‘¡ompared with the control group,hepatocellular carcinoma cells treated with kanglaite showed significant apoptosis phenomenon (P<0.05). â‘¢In microscopy, the characteristics of apoptosis such as the formation of cell-membraneblebs and apoptotic bodies, were observed morphologically inhepatocellular carcinoma cells.CONCLUSION: Kanglaite injection not only relatively high inhibition but also induces apoptosis in hepatocellular carcinoma.
Keywords/Search Tags:Kanglaite, Hepatocellular carcinoma, Proliferation, Programmed cell death
PDF Full Text Request
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