| According to the investigation on the Clonorchis sinensis distribution and harm covering 62 counties, cities and forest regions in Hubei province, it was made it clear that the Clonorchis sinensis'?, distribution in geography , characteristics and regularity in epidemic . The result is that the area of the disease was existed in 52 counties and cities, hi the 31 counties and cities, the infected people were found in 29. The rate of infection in population is from 0.1% to 16.2%. In the survey it was found that 5 species of fresh water snails are the first intermediate hosts. One of them is the new record in Hubei province. In the study of the snail's ecology, the survival time of Clonorchis sinensis^ cercaria in the body of snail is 6 months long in the middle area of this province. 7 families and 31 species fishes and 1 species of shrimp are the second intermediate hosts. The encysted metacercaria can exist in the body of the fish for at least 20 months. The ability of the encysted metacercaria causing pathogenic changes and injuries can't decrease with the extension of the lodging time. 6 kinds of domestic or wild animals are reservoir hosts.In order to increase the detection rate of the pathogen, the related medicine or fatty food was given to the infected person to increase eggs in feces by 50-150%. The ELISA and IFA evaluated the rate of infection in population. The result of fecal examination for eggs exactly accorded with a real level of infection. X-ray examination of the liver and cholecyst of the people infected with the Clonorchis sinensis in the lab was made. Rays showed the special result of infected people liver and cholecyst. A new way of diagnosis to the clonorchiasis was exploited. The way was also adapted to the light infected people to be tested by the egg number in feces.Although the distribution and every part of epidemic are complicated and serious in Hubei province, and the Clonorchis sinensis's characteristics and regularity were controlled basically in the survey. The research provided the evidence to formulate the methods. |