Prepotent Research Of The Component Of The Medicine Liquid Used In Clinical Inhaled Aerosol Therapy And Observation Of Curative Effect In Clinical

Inhaled aerosol therapy is widely used in clinic. The significant benefits lie in the directly action of the medicine, the rapid curative effect and little side effect to the whole body. It can also shorten the healing time in hospital and costs relatively cheaper. For a long time the component of the inhaled aerosol medicine liquid used by the clinical doctor comes from experience and custom, lacking of strictly test and research basis. These lead to some optional and blindfold character and affect the exertion of the therapy. Some clinic medicine in common use has been chosen for standby. They are been divided in several groups as following: mucus motivating, antibacterial action, bronchia spasmolysis, resisting inflammation and others, adjusting the physical & chemical property of solution. First of all, testing the compound of single medicine and its basic physical & chemical property, then carrying on extensive confecting trials among different types. Based on the physical & chemical properties of the medicine liquidobtained from the tests above, three group of the medicine component liquid has been recommended according to the ideal curative effect demands of aerosol medicine liquid: effectively motivating the mucus, positive effects of spasmolysis, some antibacterial actions, some effects of resisting inflammation and protecting epidermis, gentle property and accepted by patients. The No.1 component is composed of: 0.9%NaCl 2ml+NAC 2ml(100mg)+ gentamycin 2ml(80,000U)+salbutamolum aerosol solution 1ml(5mg) + 10%NaCl 2ml + 5%NaHCO3 5ml. The basic property is PH 7.7 and osmole equal 3.6%NaCl. It is mainly used in COPD acute infection period and other patients with respiratory tract acute & chronic inflammation when sputum is stiff. The No.2 component is composed of: adding ipratropium bromide aerosol liquid 1ml(0.25mg)and flutiasone propionate microfine 4 spray(200μg)to No.1 component. The basic property is PH 7.6 and osmole equal 3.5%NaCl. It is mainly used for COPD and bronchia asthma patients who gasp evidently during acute infection period. The No.3 component is: 0.9%NaCl 2ml + NAC 2ml(100mg) + ipratropium bromide aerosol liquid 1ml(0.25mg) + heparinum 1ml + fosfomycin 2ml(200mg)+10%NaCl 2ml+5%NaHCO3 5ml. The basic property is PH 7.8 and osmole equal 3.5%NaCl. This is used as COPD patients' long-term part medicine during stable period. The three top-priority components has been introduced in clinic tryout and observed. The results show that the patients accept them very well. All the components present the intent curative effect basically and display favorable application basic. Because the research provides the solution property and compatibility of clinic inhaled aerosol medicine in common use, and recommends three components for clinic usual respiratorytract sickness. The research result is expected to provide some reference for the extended clinic doctor when the inhaled aerosol therapy is adopted.