| This paper introduced the morphological character, geographic distribution, chemical constitutes, pharmaceutical function, officinal importance and exploldering forground of Forsythia Suspens . It also studied the effect of protecting liver, the oil anti-oxidative, the anti-senile, the anti-stress activity and enhancing immunological function of Forsythia Suspensa.Forsythia Suspensa vahl. Belongs to Oleaceae's degoliate shrub. It is 2~4 meters high. Its branch is unfold and the flower is yellow. Its fruits are tip and egg-shaped. Forsythia Suspensa mainly grows in Hebei province, Shanxi province, Shaanxi province, Shandong province, Henan province and so on. It mainly contains terpenes, phenylethanol, flavonoid, lignan, alcohol, ester, aldehude, ketone, volatice oil and so forth. It also contains abundant trace elements which are necessary to body, such as Cu, Zn, Fe, Mn and so on.Forsythia Suspensa is a traditional Chinese drug in China. Recent years the reports about pharmaceutical functions of Forsythia Suspensa increased as more people analysed chemical constitutes of Forsythia Suspensa. Its funtions are extensive, such as antiviral activity, antibacterial action, cardiotonic action, diuresis, protecting liver, decreasing blood pressure and so on. The popular investigation shows Forsythia Suspensa leaves have the effects of eliminating constipation, preventive popular cold, reducing blood lipid and so on. In addtion, Forsythia Suspensa can be used for keeping food fresh, eliminating unpleasant odor, preserving the earth.Traditionally the fruits of Forsythia Suspensa is regarded as a crude Chinese drug, but we can get to the conclution that the chemical constitutes of Forsythia Suspensa in leavers are the same as in fruits according to the recently analytic results about chemical constitutes of Forsythia Suspense, and the content of effective compositions, such as forsythin forsythigenol, oleanolid acid and so on, in leaves is higher than in fruits. In order to develepe and apply this natural source, the experiment trys to study pharmacological actions of Forsythia Suspensa leave tea confirm the functions, andsupply evidence for its source development and application.In protecting liver experiment, mice were injected with CCl4 to established liver induced model, ALT, AST, CHE, TBIL, TP, GSH in serum and SOD, MDA, CHE, ALB, MDA,GSH in liver were measured to confirm the ability of protecting liver of Forsythia Suspensa leaves tea. In the experiment of oil antio-xidation, lard oil with different concentrations Forsythia Suspensa leaves tea ertraction should be stored in 60 癈 oven, the antioxidant activity of Forsythia Suspensa leaves tea in lard oil was studied by using peroxide value and acid value. On study of anti-senile activity of Forsythia Suspensa leaves tea, animal model of aging was made in mice by natural aging. In order to comfirm the anti-senile activity of Forsythia Suspensa leaves tea, MDA, SOD, POD, in red blood cell, heart, LF, MDA, SOD, MAO-B in brain SOD, MDA, HYP, MAO-B in liver, SOD, MDA, MAO-B in mitochondiria and liver index, thymus index, spleen index, heart index were measured. The phagocytic function of macrophage and delayed hypersensitivity were researched to show weather Forsythia Suspensa leaves tea can enhance the immune function of mice. The anti-stress activity of Forsythia Suspensa leaves tea was studied by the survival time under the conditions of normotensive hypoxiaof mice.The results of experiments show:1. Forsythia Suspensa leaves tea can inhibit obviously the abnormal increase of ALT, AST in serum and liver, enhance SOD, CHE activity in serum and liver, increase GSH, TP, ALB content, decrease MDA formation, adjust TBIL metabolism.The results show that Forsythia Suspensa leaves tea can eliminate free radical and improve the metabolism of liver, which indicates Forsythia Suspensa leaves tea can protect injured liver.2. Forsythia Suspensa leaves tea can be used for an antioxidant, though the effect of Forsythia Suspensa leaves tea is worse than composite antioxida... |
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