The Existence State Of Lactobacillus Acidophilus 130B4 In Rat Digestive Tract And Its Effects On Blood Fat And Blood Pressure

As members of today's society advance in age, diseases along with causes of death have changed drastically. New ailments have been discovered such as hypertension. It is a serious sickness, that has inflicted numerous people. That number may increase with the possibility of young persons becoming among its victims. People came to realize the nutritious value of dairy products especially fermented milk. It has several benefits to human health. Thus, research pertinent to manner in which it improves health, has intensified. It is essential to study its positive impact upon slightly inflicted patients with hyper blood fat syndrome. It is also fundamental to develop the fermented dairy products that would prevent and control that syndrome among healthy individuals. However the function of fermented milk and its decreasing blood fat mechanism are unknown. Experiments were conducted on rats. They were fed Lactobacillus acidophilus 130B4 undiluted liquid, and fermented milk originated from this kind of liquid. The existence state of Lactobacillus in the digestive tract, its effects on serum cholesterol concentration, triglyceride (TG) concentration and its impact upon blood pressure were studied. The result could be summarized as follows:1- Lactobacillus acidophilus 130B4 was tolerant to gastric acid and bile acid. 2- Lactobacillus acidobacilus 130B4 does not affect the total serum cholesterol concentration.3-It decreases the serum TG level. 4-It limits the activity of angiotensin converting enzyme (ACE) and decrease the blood pressure to some degree. The result will establish the theoretical foundation of Lactobacillus acidophilus 130B4,which could be used as probiotics widely.