The Cross-sectional Survey On MI Patient's Pharmaceutical Therapy In Taigang Area

Objective To investigate the situation of pharmaceutical therapy for AMI in Taigang area,and provide information for further clinical practice. Methods The data of 4-year (1999-2002)in-patient cases in Taigang hospital was used for the study.SAS 8.0 software was used for statistics and analysis. Results The total of MI in-patient cases( 1999-2002) in Taigang area was 229.The total MI drug used- rate was :p-blocker 50%,ACEI/ARB 66%,tatin 5%,N 98%,asprin 93% respectively. The β -blocker used-rate per year was 1999-28%, 2000-56%, 2001-54%, 2002-47%.The ACEI/ARB used-rate per year was 1999-70%, 2000-71%, 2001-68%, 2002-47%.The proportion of β -blocker was :metoprolol 71%,atenolol 35%.The proportion of ACEI /ARB was:captopril 96%,enalapril 3%.The mean dose of metoprolol(Md) was 36mg/d( range6.25-200mg/d),the mean dose of captopril(Md) was 35mg/d(range6.25-150mg/d).The main reason of unused (3-blocker was sinus bradycardia,unused with no reason,sever hart faliure,AV block,etc.The mainreason of unused ACEI/ARB was hypotension,unused with no reason,etc. Conclusions The P -blocker used- rate had prompted in 1999-2002(p<0.05 p=0.0141= .The ACEI /ARE used-rate was steady in 1999-2001,but droped in 2002(p>0.05 p=0.0885),without statistical signification.The lower tatin used- rate was due to lack of knowledge.The most frequent p-blocker was metoprolol; The most frequent ACEI/ARB was catopril,that hadn't changed to enalapril.The mean dose of metoprolol was a bit lower than the instruction in our country.The mean dose of captopril was fit to the instrction in our country.The unused-rate of (3-blocker without any reason was 23%,the unused- rate of ACEI /ARE without any reason was 35%.So the rational drug use in MI patients should be given more concern .