Effects Of Intravenous Remifentanil Used In Cesarean Section On The Parturient And Neonate

Objective: Remifentanil has been a little studied in obstetric patients. This study observes the effects of remifentanil administered as an intravenous infusion in combined spinal-epidural anesthesia (CSEA) for cesarean section on the parturient and neonate.Methods: Sixty healthy parturients undergoing elective cesarean section with CSEA were randomly designed into three groups, each group 20 patients. Group C (control group) received saline intravenously. Group R₁ received 0.05μg·kg^-1·min^-1 remifentanil intravenously, and group R₂ received 0.1μg·kg^-1·min^-1 remifentanil intravenously. Maternal vital signs were monitored, and sedation levels were assessed at skin incision. Maternal arterial (MA), umbilical arterial (UA), and umbilical venous (UV) blood samples were obtained at delivery for blood gas analysis. Apgar scores were assessed at 1 and 5 minute. Side effects of parturients and newborns were...