The Clinical Study Of The Relation Between Metabolic Syndrome Complicated By Acute Coronary Syndrome And Coronary Artery Lesions

Objective:To investigate the relation between metabolic syndrome (MS) and acute coronary syndrome (ACS) and the features of coronary artery lesions by coronary angiography .Methods:The epidemiology features of MS and ACS were analysed among 311 patients, who had been diognosed as possible coronary heart disease after removing the primary cardiomyopathy and congenital coronary dysplasia. The 50 patients of snoring were divided into Obstructive Sleep Apnea Syndyome(OSAS)group(n=18) and non-OSAS group(n=32) and the incidence of MS is analysed. 311 patients by coronary angiography were divided into MS group(n=186) and non-MS group (n=125) and the incidence of ACS, coronary artery lesions, coronary vasodilation and the coronary slow flow were compared. 73 ACS patients were divided into MS group(n=51) and non-MS group (n=22) and the incidence of the multi-artery lesions , serious coronary stenosis , chronic total occlusions, long coronary lesions, ostial stenosis and bifurcation lesions were compared. After removing sachaxometabolic disorder, 242 patients were divided into MS group(n=126) and non-MS group (n=116) and the incidenceof ACS complex coronary artery lesions were compared again. Results:The incidence of MS and ACS was 59. 8% and 23. 5% respectively. The incedenceof MS in the OSAS group was more than in the non-OSAS group (66. 7% vs 34.4%). The incedence of ACS -. coronary artery lesions -, coronary vasodilation and the coronary slow flow in the MS group were more than in the non-MS group (27. 4% vs 17. 6%, 64.0% vs 43. 2%, 16. 1% vs 8. 0%, 29. 6% vs 16. 0%). Among the ACS patients, the incidence of the lesions of the multi-artery, serious coronary stenosis, chronic total occlusionsN long coronary lesions, bifurcation lesions and ostial stenosis in the MS group were more than in the non-MS group (45.1% vs 18. 2%, 56. 9% vs 31.8%. 31. 4% vs 9.1%, 58. 8% vs 31. 8%, 23. 5% vs 9.1%, 45.1% vs 18. 2%). After removing sacharometabolic disorder, the incidence of ACS % the lesions of the multi-artery, serious coronary stenosis, chronic total occlusions, long coronary lesions> bifurcation lesions and ostial stenosis in the MS group were still more than in the non-MS group(27. 0% vs 16.4%, 16. 7% vs 7.8%, 28. 6% vs 17. 2%, 15. 1% vs 6. 0%, 18. 3% vs 8. 6%, 9. 5% vs 2. 6%, 19.8% vs 10. 3%.Conclusions: Among the patients who are diognosed as possible coronary heart disease, MS can accelerate the occurrence and development of ACS. Patients with MS complicated by ACS would have serious ang complex coronary artery lesions. Deepening our understanding and interference of MS is an important pathway of prevention and treatment of coronary heart disease. While paying a good deal of attention to the sacharometabolic disorder, we should also tackle comprehensively the mutiple risk factors of cardiovascular disease.