Before And After Surgical Valve Replacement To Evaluate Effects Of Valve Dysfunction On Tei Index

Objective: This study was designed to compare Tei index before and after surgical valve replacement to evaluate effects of valve dysfunction on Tei index.Methods: Participants consisted of 86 consecutive patients with aortic or mitral valve surgery (21patients with aortic stenosis (AS),17 with aortic regurgitation,28 with mitral stenosis, and 20 with mitral regurgitation) .left ventricular ejection fraction (LVEF) ,fractional shortening (FS),left ventricular end-diastolic dimension (LVDd),left ventricular end-systolic dimension (LVDs), left atrial dimension (LAD),and Tei index were measured by transthoracic echocardiography 1 week to 1 month before surgery , 1 week to 1 month, after surgery .Doppler Tei index was evaluated before and after the surgery by obtaining (a-b)/b, where "a" is the interval between the cessation and onset of Doppler mitral filling flow and "b" is the aortic flow ejection time.Results: Tei index significantly increased after surgery in patients with aortic stenosis ,aortic regurgitation ,and mitral stenosis;the difference were significant (p<0.01).Tei index decreased with no significance in mitral regurgitation (p>0.05). There were statistical difference in all other measurements but not all the parameters were different. Percent change in Tei index after valve surgery was maximal in patients with As.Conclusion : Tei index significantly changes after valve surgery especially in patients with As, Considerations for the effects of valve dysfunction on Tei index are required for its application to evaluate ventricular function in patients with valve disease.