Experiment Research On The Morphology Of Geotrichum Silvicola And Its Sensitivity To Antifungal Agents In-vivo

Objective: Geotrichum sivicola, a new strain in Geotrichum, was first isolated from Brazil fly and Indian oak silkworm in 2002. Then it was isolated from a children's kerion-like lesions and a patient's blood suffered with toxic epidermal necrolysis one after another in our department. The morpholgy and susceptibility test in vitro of the skin isolation has been studied.In our research, blood isolation was observed with full-scale for further understanding of characteristics on morphology and vegetative production of Geotrichum sivicola which can help clinical docters to establish diagnosis on the infection of Geotrichum silvecola. Further more,to provide the guidance on the treatment of systemic infection of Geotricum sivicola, Fluconazol, Itraconazole and Terbinafine were emploied agaist the systemic infection of Geotricum sivicola of immunodepressed mouse model.Methods: 1 Sequence analysis of DNA Extract DNA of blood isolation and amplify the domain D1/D2 of its 26SrDNA, determin its site of basic group through DNA automatic sequencer, then...