Initial Study On Multifocal Visual Evoked Potential (Multifocal VEP) Of Optic Neuritis

OBJECTIVE: To investigate the wavelet character in the same ring according to the different eccentricity distribution in the multifocal visual evoked potential of optic neuritis;Tracking the local damage to the optic nerve after outbreak of optic neuritis and the recovery after treatment,so offer the objective way of the early diagnosis , the effects of treatments and the monitor of prognosis. METHOD: Carry on the multifocal VEP examination to 30 eyes with thirty cases of optic neuritis,and adopt to contrast the sick eyes and the nomal eyes in the same patients and the 30 eyes of fifteen normal individuals,mainly analysis the multifocal VEP Second-order kernel response ,according to the diffent ring in the same heart,analysing each reaction total wave,carrying on the comparison to each ring.RESULTS: Before treatment the sick eyes contrast to the normal eyes in the same patients,the latencies of p-wavelet were lengthened ,and the amplitudes of p-wavelet were lowered (p<0.05).Contrast the before treatmeat of the sick eyes to the after treatment ,the latencies of p-wavelet have the improvement of different degree (p<0.05),and the amplitudes of p-wavelet have the obvious difference(p<0.05),all of the amplitudes recover the normal after treatment.After treatment the sick eyes contrast to the normal eyes in the same patients, the amplitudes of p-wavelet have no obvious difference(p>0.05),the latencies of p-wavelet still have the obvious difference(p<0.05).CONCLUSION: The multifocal VEP can apply the early diagnosis of optic neuritis,and the effects of treatments,and have the obvious advantage in estimating the local damage to the optic nerve and tracking the recovery of damage of the optic nervecontrasting to visual field or the traditional VEP.