Forceps And Brush Biopsy Diagnosis Of Suspected Of Having Malignant Biliary Obstruction During PTCD

Objective : To evaluate percutaneous transhepatic forceps and brush biopsy in patients suspected of having a malignant biliary obstruction.Methods : There were 21cases of obstructive jaundice, male 14 cases,female 10 cases,40-93 years old, mean 69.2years old. All the patients in this study underwent percutaneous transhepatic forceps and brush biopsy during PTCD. In each patient ,two to three specimens were taken from the lesion with biopsy foeceps.Results : The forceps biopsy was performed in all cases., the brush biopcy was performed in 14 cases at same time. Nineteen of twenty four patients resulted in a cancer diagnosis. Adenocarcinoma was found in 15cases ;atypia was found in 4 cases; inflammatory was found in 2 cases. The others were negative. 4 positive results were find in brush biopsy. The sensitivity rate of forceps biopsy was 79.2%; and the sensetivity rate of brush was 28.5% .No major complications related to the biopsy and brush procedures occurred.Conclusion : Percutaneous transhepatic forceps and brush biopsy is a safe procedure that is easy to perform .It provides relatively high accuracy in the diagnosis of malignant biliary obstructions.