Short-term And Long-term Therapeutics Effects Of Varying Treatment Methods In Patients With Acute Myocardial Infarction: A Comparison Study

Objectives : To explore the safety,the efficacy and the value of primary percutaneous coronary intervention in acute myocardial infarction, through the study of recent effect and long-term prognosis in different kinds of therapy for 338 patients of acute myocardial infarction.Methods : All 338 patients with acute myocardial infarction were hospitalized patients in the Medical Department of cardiology of The First Hospital Affiliated to Suzhou University from the year2001 to 2005.An average period of followed up time is 8-56 months,The mortality rates, myocardial infarction, or target vessel revascularization ,angina pectoris, Cardiac function were observed.The following up rate was 85.5% and 289 patients were enrolled. 289 patients with AMI were assigned to four groups according to different kinds of therapics: 1, Primary Percutaneous Coro- nary Intervention group(96 patients),The group were subdivided into primary stent implantation group(78 patients) and Percutaneous Transluminal Coronary Angiplasty group(18 patients); 2, Elective Percutaneous Coronary Intervention group (63 patients); 3, Intravenous thrombolytic therapy group(34 patients); 4, General treatment group(96 patients).The Short-term and Long-term Therapeutics Effects (the morta- lity, incidence rate major adverse cadiac event and complication) were compared, retrospectively.Results : 1, There was no significant difference in Sex, complicating hyperten- sion, diabetes, old myocardial infarction, infarct location, left ventricular ejection fraction, Killip's grading and general treatment among the four groups (P>0.05). There was also no significant difference in Coronary angiography, Infarcted relative artery, Thrombolysis in myocardial infarction grading, achievement ratio between the twe groups (Primary PCI group and Elective PCI group). Age in the Primary PCI group was higher than the Elective PCI group(P<0.05),while there is no apparent difference in age among other three groups(P>0.05); 2, Percutaneous Coronary Intervention and Intravenous thrombolytic therapy in patients with acute myocardial infarction can decrease in- hospital mortality , the primary PCI group (4.2%), the elective PCI group(4.8%), the thrombolytic therapy...