The Study Of Relationships Between Serum C-Reactive Protein,the Activity Of Fibrinolytic System In Acute Cerebral Infarction And Different Type Of Syndrome Of TCM

Objective: To observe the expression levels of serum C-Reactive Protein(CRP), tissue-type plasminogen activator(t-PA), plasminogen activator inhibitor(PAI-1) and the ratio of t-PA/PAI-1 in acute cerebral infarction(ACI), explore the relationships between serum CRP, the activity of fibrinolytic system and ACI's different types of syndrome of TCM, offer micro indexes of ACI's differentiation of symptoms and signs of TCM.Methods: 90 patients were divided into three groups:wind phlegm blood stasis type group (30 patients), deficiency of vital energy blood stasis type group (30 patients) and yin asthenia wind move type group (30 patients). 30 healthy people were included in normal control group. We detect the levels of serum CRP by immunizing scattering ratio neph, t-PA and PAI-1 by enzyme linked immunosorbent assay(ELISA).Results:1. The levels of CRP, t-PA and PAI-1 increased obviously and the ratio of t-PA/PAI-1 dropped obviously in ACI patients, which had significant difference(P<0.01 or P<0.05) compared with control group.2. Positive correlation (r=0.391,P<0.01) was obtained by correlation analysis between the levels of CRP and PAI-1 in ACI patients, but there is no correlation between the levels of CRP and t-PA or the ratio of t-PA/PAI-1.3. The contents of CRP : wind phlegm blood stasis blocking type group > qi deficiency blood stagnancy type group > yin deficiency wind stirring type group. There exist significant...