Experimental Studies On Pharmacodynamics And Acute Toxicology Of The Root And Leaf Of Panicled Fameflower

Objective: The root and leaf of Panicled Fameflower have been come forth in the towmspeple' s table of the southeast of Fu Jian, but there are rarely studied through experiment. This study will assess elementarily the security and effectiveness of The root and leaf of Panicled Fameflower through the experimental studies on their pharmacodynamics and acute toxicology, provid possibly theorems and experimental foundations for Panicled Fameflower' s edibleness, planting and study.Methods: â‘ Pharmacodynamics observed the effects of The root and leaf of Panicled Fameflower on swimming time of mouse, and physiological function, IL-2 IgA IgM IgG C3 C4 of rat of asthenia of the spleen, and The leaf of Panicled Fameflower on determinating mininal inhibitory concentration (MIC), swelling of mouse ear, capillary vein permeability of mouse skin, granuloma in rat. â‘¡Trial of acute toxicity: The mouse were given once the drugs of The root (10g/ml)and leaf (9g/ml) of Panicled Fameflower by irrigating gastric in largest volume (0.3ml/10g). If the mouses died, 50% lethal dose (LD₅₀) was measured. When LD₅₀ not measured out because of lower toxicity, the maximum tolerance dose (MTD) was measured with the highest concentrationand the largest volumeby irrigating gastric(ig) for 3 times in one day.Results:In the increasing avoirdupois, enhancing growth and development of...