Effect Of Jiusuyu On Neurotransmitter And Oxidative Damage Of Acute Alcoholism Mice In Brain

Objective: This paper aims to verify the curative effect that Jiusuyu cure the acute alcoholism disease by counting the changes of ebriety time, ebriety rate, sober-up time death rate, and discuss the effect of neurotransmitter and oxidative damage on acute alcoholism mice in brain tissue by examining the changes of SOD, MDA, DA, 5-HT, AchE in btain tissue.Methods:Part 1: The Pharmacology research of acute alcoholism mice with Jiusuyu.1. The effect of Jiusuyu on ebriety rate, ebriety time of acute alcoholism mice observed after preventing treatment80 healthy mice, bisexual and each half, were randomly divided into 4 groups, 20 mice every group, named model group (equal volume physiological saline were given through the means of watering stomach), low-dose group of Jiusuyu (called low-dose group, 1.62g/100g avoirdupois Jiusuyu drinked through the means of watering stomach), high-dose group of Jiusuyu (called high-dose group, 3.24g/100g avoirdupois Jiusuyu drinked through the means of watering stomach), and Gehuajiecheng liquid control group(called control group, 1.31g/100g avoirdupois Gehuajiecheng liquid were drinked...