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Expression Of Centromere Protein F (CENP-F) In Human Brain Glioma And Its Significance

Posted on:2007-01-17Degree:MasterType:Thesis
Country:ChinaCandidate:B C ChengFull Text:PDF
GTID:2144360185979206Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: Human brain glioma is frequent one of the intracranial tumors, occupied 50% in the tumors of the central nervous system. Their incidence rate of the whole crowd is 100 thousand of 4. Most of glioma are the invasive and infiltrative growth malignant tumors, radical cure is scarcely carried out/ got by only operation, even if we have taken the combined therapy, example radiotherapy, chemotherapy, 70% and 52% of them are recrudescent and dead in 5 years. Up to now, because the etiopathogenesis of the human brain glioma have been not discoveried. effective modus have been not got in radical cure, most of them have still threatened human being's life and health. Cell cycle is the universal process by which cells reproduce. It underlies the growth and development of all living organisms. The most important events of the cell cycle are those concerned with the duplicating and partitionining of the hereditary materials. In other words, that is replicating the genomic DNA during S phase and separating the replicated genomes into tow daughter cells during mitosis. The onset of these events was regulated faithfully and delicately, and errors in their execution can and must be repaired to prevent catastrophic outcome. These events are height conservative fromthe monoplast yeast to the secondary human being in all eukaryote. Precise regulation in the cell cycle events can guarantee the survivorship and multiply of the life. Precise regulation in the cell cycle events can guarantee the survivorship and multiply of the life. Timorous risk is accrescence, while loss of the precise regulation. The chromosome movements and separation during cell cycle. Recent years, tumors have been considered for the cell cycle related disease. The essence of the malignant tumor is the loss of...
Keywords/Search Tags:Centromereprotein F, Glioma, Malignant Proliferation, Immunohistochemistry
PDF Full Text Request
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