Influence Of Acute Hypervolemic Hemodilution Combined With Controlled Hypotension On The Balance Of Oxygen Providing And Consumption In Brain

Objective To observe the influence of acute hypervolemic hemodilution(AHH) combined with controlled hypotension(CH) on the balance of oxygen providing and consumption in brain. Methods Twenty ASA â…  ～ â…¡ patients who were not undergoing heart surgery were randomly divided into two groups: AHH+ CH group (groupH,n=10) and control group(group C,n=10). Jugular venous and radial artery blood was synchronously obtained, blood gases was analyzed,and CEO₂ and Da-jvO₂ were calculated before AHH(T₀), 10min(T₁), 30min(T₂)and 60min(T₃)after AHH was performed. Results AHH can maintain hemodynamic stability during CH in all patients, CVP of group H increased, and they were still in normal range.There was no significant difference between group H and group C in HCT before AHH; HCT in group H decreased significantly in T₁,T₂and T₃ compared with T₀, in T₁, compared with group C, SjvO2 increased especially in T3₃ and CEO₂, Da-jvO2₂ decreased especially in T₂ ,T3₃ in group H after AHH. SjvO₂ in group H were higher those in group C especially in T₁. Conclusion There were no influence of acute hypervolemic hemodilution combined with controlled hypotension on the balance of oxygen providing and consumption in brain.AHH can also improve oxygen comsumpation in brain during CH.