Experimental Research Of Resuscitable Treatment Against Sleep Deprivation And Development Of Automatic Sleep Deprivation Recorder In Rats

Objective: Sleep deprivation means a state that the necessary sleepness is lost because of physiological, pathological or environmental reasons. With the crazy pace of modern society, as well as the requirement in some special departments, sleep deprivation becomes more and more common and unhealthy to human beings. By now, the drugs used to anti sleep deprivation usually act on center nerve system and would bring much badness when used a great deal or for a long time, which could not be used without permission from government. So, based on the study of the function of sleepness, the badness of sleep deprivation, the superiorities and shortcomings of the drugs used to treat sleep deprivation and the corresponding theory in Traditional Chinese Medicine, we developed a new drug made mainly of grassleaved sweetflag rhizome and borneol-Resuseitable nasal drops. The objections of this article were as follows: to study the actions of Resuscitable nasal drops against sleep deprivation; to explore the effecting mechanism of the new drug ;to evaluate the application of automatic sleep deprivation recorder in rats, in order to make it applied widely.Methods: 1. Mice, divided randomly into five groups:normal control group, pathological pattern group, high-dosage group, middle-dosage group, and low-dosage group. Every groups were breeded separately for a whole week before experiment. To administer with nasal drugs by homemade nasal instrument. Once...