Studying The Relationship Between Deficiency Of Both Qi And Yin Syndrome And Its Related Index Of ET Et With Diabetic Artery Obliterans

Objective: To study the relation between deficiency of both Qi and Yin(DBQY) of diabetic artery obliterans(DAO) and ET, TXB₂. 6-Keto-PGF_1a and blood lipid. This provide relevant data for studying syndrome differentiation typing. Method: 48 DBQY of DAO cases were randomly divided into two groups: 23 cases belonged to DBQY with cold-damp group and 25 cases belonged to DBQY with stasis group. 23 normal people were selected as control group. Blood lipid indexes were measured using enzyme-linked immunosorbent assay. Others were measured using radioimmunoassay(RIA). Results: (1)The levels of ET, TXB₂, TC, TG and LDL in DBQY of DAO cases were significantly higher than those of controlled group(P<0.05). The levels of 6-Keto-PGF_1a and HDL declined significantly (P<0.05). (2) In DBQY of DAO cases,the concentration of indexes were in the following sequence: ET: DBQY with stasis group>DBQY with cold-damp group(P<0.05); TXB₂ also has this effect(P<0.05); but 6-Keto-PGF_1a is contrary, DBQY with stasis group0.05). Conclusion: (1)The marked increasing ET show that DAO patients have the degree of collateral damage.(2)The changes of TXB₂ and 6-Keto-PGF_1a indicate that there exists obvious blood stasis in DAO patients.(3)According to the existence of blood lipid disorder, blood lipid metabolism also lead stasis.