Cross-sectional Study And Analysis Of High-Normal Blood Pressure Of Officials In Some City In Hunan Province

Objectives: to describe the current prevalence of high-normal bloodpressure of officials in some city in Hunan Province throughcross-sectional investigation, to explore relationships betweenhigh-normal blood pressure and risk factors, to quantify and assessinfluences on high-normal blood pressure by risk factors, and to provideevidences for making strategies of prevention and treatment.Methods: Through multistage sampling, a resident group of 3651officials in some city in Hunan Province was selected for across-sectional investigation from January to March in 2007.Questionnaire, physical examinations and laboratory tests were carriedout; then general descriptive analysis was adopted, followed bymultinomial logistic analysis with blood pressure as a dependent variable,independent variables internalized including age, sex, body mass index(BMI), blood fat, fasting blood sugar (FBS), serum creatinine (CREA),blood uric acid (UA), smoking, drinking and family history ofhypertension; finally logistic models were built to analyse and compareinfluences of correlation factors.Results: 1. The prevalence of high-normal blood pressure was42.54%, 10.44% higher than national average level, males 47.47% andfemales 32.73%, respectively. The prevalence of hypertension was22.87%, 4.07% higher than national average level, males 27.21% andfemales 14.24%, respectively.2. People with high-normal blood pressure had higher levels of BMI,FBS, TC, LDL-C, TG, UA, CREA, BUN, higher ratios of smoking anddrinking and lower level of HDL-C than people with normal bloodpressure (P＜0.05). 3.93% had four or more cardiovascular risk factors ofpeople with high-normal blood pressure, 9.01% three, 21.31% two,24.60% one, none 41.15%.3. Correlation of high-normal blood pressure and risk factors:(1) High-normal blood pressure was correlated with age, BMI, bloodfat, CREA, BUN, family history of hypertension (P＜0.001).(2) Sex: the prevalence of males was higher than females (P＜0.001) while there was no significant sexual difference in people withhypertension.(3) UA: the prevalence of high-normal blood pressure wassignificantly higher in people with hyperuricemia than the ones withnormal UA (P＜0.05).(4) FBS: correlation of FBS and high-normal blood pressure wasshowed in univariate multinomial logistic regression analysis (P＜0.05)but not in multivariate multinomial logistic regression analysis (P＞0.05).(5) CREA: no significant correlation was showed of CREA andhigh-normal blood pressure or hypertension (P＞0.05).4. Influences of risk factors on high-normal blood pressure:(1) Age: people aged over 70 were 2.1-8.6 times as likely as the onesaged 30-39 to get high-normal blood pressure.(2) BMI: obesity increased relative risk of getting high-normal bloodpressure for 2.4-12.5 times.(3) Smoking: smokers were 2.5-9.1 times as likely as non-smokers toget high-normal blood pressure.(4) Drinking: drinking increased relative risk for 5.6-11.5 times.(5) Other risk factors: male (OR=1.460), lipid abnormalities(OR=1.258), hyperuricemia (OR=1.724) and family history ofhypertension all increased relative risk.Conclusions: 1. The prevalences of high-normal blood pressure andhypertension were higher in officials in Changsha than national averagelevels.2. One or more cardiovascular risk factors existed in 58.85% ofpeople with high-normal blood pressure, 24.60% one, 21.31% two,9.01% three.3. Age, obesity, smoking, drinking and other risk factors werecorrelated with high-normal blood pressure, and the former four couldsignificantly increase its relative risk, which indicated that interventiontowards risk factors was essential for treating high-normal blood pressure.