Relationship Between The Infections Of HBV And HCV In Korean And Han Male Patients With Primary Hepatocarcinoma In Yanbian Area

Objective: To investigate the infection of HBV and HCV in Korean and Han male patientswith primary hepatocarcinoma (PHC) in Yanbian area.Methods: A total of 889 patients with PHC (Korean male/famle; n=537/126, Han male/female: n=179/47) were included in the study and compared analyze the markers of hepatitisB virus (HBV M) and anti HCV antibody of serum in 503 cases of Korean male and 169cases of Han male in PHC with non PHC HBV M control group.The alcohol consumptionwas also analysed between the Korean and Han male patients with PHC.Results: The male/female ratio was 4.26:1 in Korean and was 3.81:1 in Han with PHC.Theinfection ratio of HBV was 53.3％, HCV was 24.3％and coinfection of HBV and HCVwas15.1％in Korean male, and HBV was 64.5％, HCV was 18.93％, and coinfection ofHBV and HCV was 10.1％in Han male with PHC, respectively. There were significantdifferences between infection ratio of HBV, HCV and coinfection (x~2=6.930, P＜0.05) inKorean and Han male. The combination of HBsAg,HbeAb,and HbcAb positive model waspresented 51.6％, 43.56％, the HBsAg and HbcAb positive models was presented 23.84％,28.71％, the HBsAg, HbeAg, and HbcAb positive model was presented 13.37％, 13.86％inKorean and Han male,respectively. There were significant differences compared with thenon PHCs HBV M control group (x~2=113.593, P＜0.001,x~2=93.608, P＜0.001). The rateof heavy drinkers was higher in Korean than the Hart male (48.23％,35.75, x~2=8.585,P＜0.05).Conclusion: The HBV infection is a major etiologic for with PHC in Korean and Hart male, follow isthe HCV infection. The infection ratio of HBV and HCV was different between two nationalites male.The combination positive of HBsAg, HbeAb, and HbcAb, HBsAg, and HbcAb model were the PHCshigh-risk groups. The number of PHC was more in Korean than Han male may be associated with theheavy drinker.